Ciprofloxacin
NOTE: all such reactions are rare.
(known and reported, not all may be current.)
|
Ciprofloxacin |
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|---|---|---|---|---|---|---|---|---|
| Biological agents targetted | Anthrax, Dysentery, Legionnaire's disease,Typhoid, Yersinia enterocolitica, | |||||||
| Generally effective against | Broad spectrum antibiotic effective against Gram-positive and Gram-negative bacteria. Often used when other antibiotics fail. | |||||||
| Available forms | Oral tablets, oral suspension, intravenous solution, opthalmic solutions (in mixtures with antiinflammatory steroids.) Usually as the hydrochloride. | |||||||
| Indications and usage | Recommended for use against against a wide variety of infections when susceptibility is demonstrated. Specific dosage regimes are at the discretion of the attending physician acting on information from the manufacturer and the national authority for drug safety and use. Suggested dosages for specific agents may be on the individual agent pages, | |||||||
| Contraindications | Any previous adverse reaction to Ciprofloxacin. Avoid giving to adolescents, pregnant or lactating women, those with known neurological problems. | |||||||
| Drug interactions | Ciprofloxacin interacts with anti-asthmatic drug theophylline (also a component of caffeinated drinks) and can cause respiratory failure, seizures and cardiac arrest. Caffeinated drinks should be avoided. Patients should avoid taking ciprofloxacin with antacids. | |||||||
| Adverse
reactions and side effects
NOTE: all such reactions are rare. |
Neurological side effects ranging from dizziness to tremors, hallucinations, psychosis and convulsions have been seen in small numbers of patients. As with many other antibiotics it can kill the healthy bacteria of the gut and give rise to a disorder called pseudomembranous colitis. It can also make users sunburn easily and can cause muscle or tendon inflammation or damage. | |||||||
| Mode of action | Ciprofloxacin inhibits an enzyme called DNA gyrase that is an essential component of the mechanism that passes genetic information onto daighter cells when a cell divides. | |||||||
| Structure | |
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| Chemical names | 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid | |||||||
| CAS Registry number | 85721-33-1, 93107-08-5 (the hydrochloride) | |||||||
| (known and reported, not all may be current.) |
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| Trade Name | Country | |||||||
| Afenoxin | Unknown | |||||||
| Alcon Cilox | Colombia, Indonesia | |||||||
| Argeflox | Unknown | |||||||
| Aristin C | Unknown | |||||||
| Bacquinor/Baquinor | Indonesia | |||||||
| Baflox | Colombia | |||||||
| Baycip | Spain | |||||||
| Bayterin | Unknown | |||||||
| Belmacine | Unknown | |||||||
| Bernoflox | Indonesia | |||||||
| Biamotic | Unknown | |||||||
| Carmicina Medicor | Unknown | |||||||
| Cenin | Unknown | |||||||
| Ceprimax | Unknown | |||||||
| Cetraxal | Guatemala, Honduras, Panama, Spain | |||||||
| Ciflobac | Unknown | |||||||
| Ciflosin | Unknown | |||||||
| Ciflox | France | |||||||
| Cifloxin | Thailand | |||||||
| Cifran | Benin, Burkina Faso, Ethiopia, Gambia, Ghana, Guinea, India, Ivory Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger,Senegal, Setchelles, Sierra-Leone, Sudan, Tanzania, Tunisia, Uganda, Zambia, Zimbabwe | |||||||
| Cigram | Unknown | |||||||
| Cilab | Thailand | |||||||
| Ciloxacin | Unknown | |||||||
| Ciloxan | United States | |||||||
| Ciloxin | Unknown | |||||||
| Cimogal | Mexico | |||||||
| Ciplox | Bahrain, Benin, Burkina Faso, Cyprus, Egypt, Ethiopia, Gambia, Ghana, Guinea, Iran, Iraq, Israel, Ivory Coast, Jordan, Kenya, Kuwait, India, Lebanon, Liberia, Libya, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Oman, Saudi Arabia, Senegal, Seychelles, Sierra Leone, South Africa, Sudan, Syria, Tanzania, Tunisia, Uganda, United Arab Emirates, Yemen, Zambia, Zimbabwe | |||||||
| Ciplus | Korea | |||||||
| Ciprecu | Ecuador | |||||||
| Ciprinol | Bulgaria, Hungary | |||||||
| Cipro | United States | |||||||
| Ciprobay | Bahrain, Bulgaria, Cyprus, Czech Republic, Egypt, Germany, Hungary, Iran, Iraq, Israel, Jordan, Korea, Kuwait, Lebanon, Libya, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, South Africa, Syria, Thailand, United Arab Emirates, Yemen, | |||||||
| Ciprobay Uro | Germany | |||||||
| Ciprobid | Bahrain, Benin, Burkina Faso, Cyprus, Egypt, Ethiopia, Gambia, Ghana, Guinea, Iran, Iraq, Israel, Ivory Coast, Jordan, Kenya, Kuwait, India, Lebanon, Liberia, Libya, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Oman, Saudi Arabia, Senegal, Seychelles, Sierra Leone, South Africa, Sudan, Syria, Tanzania, Tunisia, Uganda, United Arab Emirates, Yemen, Zambia, Zimbabwe | |||||||
| Ciprobiotic | Dominican Republic | |||||||
| Ciprocinol | Bulgaria | |||||||
| Ciprodar | Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Ivory Coast, Jordan, Kuwait, Lebanon, Libya, Oman, Qatar, Saudi Arabia, United Arab Emirates, Yemen | |||||||
| Ciproflox | Bulgaria, Mexico | |||||||
| Ciprofur | Unknown | |||||||
| Ciprogis | Israel | |||||||
| Ciprolin | Peru | |||||||
| Ciprolon | Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Ivory Coast, Jordan, Kuwait, Lebanon, Libya, Oman, Qatar, Saudi Arabia, United Arab Emirates, Yemen | |||||||
| Ciprolona | Unknown | |||||||
| Ciprolox | Unknown | |||||||
| Cipromycin | Greece | |||||||
| Ciproquinol | Portugal | |||||||
| Ciproval | Unknown | |||||||
| Ciproxan | Japan | |||||||
| Ciproxin | Australia, Austria, Denmark, Finland, Greece, Indonesia, Ireland, Italy, Israel, Netherlands, New Zealand, Norway, Sweden, Switzerland, Taiwan, United Kingdom, | |||||||
| Ciproxina | Costa Rica, Dominican Republic, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Portugal | |||||||
| Ciproxine | Belgium | |||||||
| Ciprowin | India | |||||||
| Ciriax | Peru | |||||||
| Ciriopan | Unknown | |||||||
| Citopcin | Korea | |||||||
| Citrovenot | Unknown | |||||||
| Cixan | Colombia | |||||||
| Corsacin | Indonesia | |||||||
| Cosflox | India | |||||||
| Cunesin | Unknown | |||||||
| Cycin | Korea | |||||||
| Cyprobay | Mexico | |||||||
| Cyrocin | Unknown | |||||||
| Disfabac | Unknown | |||||||
| Estersina | Mexico | |||||||
| Fimoflox | Indonesia | |||||||
| Flociprin | Unknown | |||||||
| Flugram | Unknown | |||||||
| Flunase | Unknown | |||||||
| Forterra | Unknown | |||||||
| Girabloc | Unknown | |||||||
| Giraprox | Unknown | |||||||
| Giroflox | Unknown | |||||||
| Globuce | Unknown | |||||||
| Grenis Cipro | Unknown | |||||||
| Grifociprox | Unknown | |||||||
| Huberdoxin | Unknown | |||||||
| Inkamil | Unknown | |||||||
| Intermil | Unknown | |||||||
| Interflox | Unknown | |||||||
| Ipiflox | Indonesia | |||||||
| Keefloxin | Unknown | |||||||
| Kenzoflex | Mexico | |||||||
| Klicina | Unknown | |||||||
| Laboquin | Unknown | |||||||
| Ladinin | Unknown | |||||||
| Lambetrol | Unknown | |||||||
| Limox | Unknown | |||||||
| Loxan | Ecuador | |||||||
| Medociprin | Thailand | |||||||
| Megaflox | Unknown | |||||||
| Microrgan | Unknown | |||||||
| Mitroken | Mexico | |||||||
| Nivoflox | Mexico | |||||||
| Novidat | Unknown | |||||||
| Ofitin | Unknown | |||||||
| Opthaflox | Thailand | |||||||
| Plenolyt | Unknown | |||||||
| Probiox | Peru | |||||||
| Procin | Unknown | |||||||
| Proflaxin | Costa Rica, Nicaragua | |||||||
| Proflox | Thailand | |||||||
| Proksi 250 | El Salvador, Guatemala, Honduras | |||||||
| Prokisi 500 | El Salvador, Guatemala, Honduras | |||||||
| Proxacin | Unknown | |||||||
| Quidex | Unknown | |||||||
| Quinobiotic | Unknown | |||||||
| Quinolide | El Salvador, Guatemala, Honduras | |||||||
| Quinopron | Unknown | |||||||
| Quintor | India | |||||||
| Quipro | Unknown | |||||||
| Rancif | Indonesia | |||||||
| Ravalton | Unknown | |||||||
| Remena | Unknown | |||||||
| Renator | Unknown | |||||||
| Revion | Unknown | |||||||
| Rigoran | Unknown | |||||||
| Roxin | Unknown | |||||||
| Roxytal | Colombia | |||||||
| Rubrum | Unknown | |||||||
| Sanset | Unknown | |||||||
| Scanax | Unknown | |||||||
| Sepcen | Unknown | |||||||
| Septicide | Peru | |||||||
| Septocipro | Unknown | |||||||
| Sifloks | Unknown | |||||||
| Sinaflox | Unknown | |||||||
| Siprobel | Unknown | |||||||
| Sophixin Ofteno | Mexico | |||||||
| Spitacin | Korea | |||||||
| Superocin | Taiwan | |||||||
| Tam | Unknown | |||||||
| Tequinol | Unknown | |||||||
| Tigina | Unknown | |||||||
| Ultracina | Unknown | |||||||
| Velmonit | Unknown | |||||||
| Unex | Ecuador | |||||||
| Uniflox | France | |||||||
| Xorpic | Unknown | |||||||
| Zolina | Unknown | |||||||
| Zolmic | Unknown | |||||||
| Zumaflex/Zumaflox | Indonesia | |||||||
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